Drug Discovery Book

In their novel approach to Drug Discovery, Maxwell and Eckhardt explore their thesis that the discovery of new drugs-especially of innovative therapeutic agents-is an independent dynamic process that demands the full attention of researchers, rather than a spontaneous consequence of investigative research. Faced with a dearth of quantitative information on how and where innovative drugs were discovered, the authors have developed considerable quantitative data about this process in order to provide a deeper understanding of its true nature.

Drug Discovery: A Casebook and Analysis offers a unique quantitative survey of research since World War II that led to the development of 32 innovative therapeutic agents. Factual and concise, each chapter presents a review of the original scientific contributions associated with the discovery of a specific drug. These chapters are followed by a computer analysis of important variables and finally by an interpretation. Drug categories discussed include: • cardiovascular and renal (including renal transplantation) • psychiatric • neurological • rheumatological • anesthesiological • pulmonary • gastrointestinal.

Everyone interested in the basic or clinical research leading to important drugs-and the institutional interplay inherent in the process-will find Drug Discovery: A Casebook and Analysis a comprehensive, invaluable reference compendium!

Booknews

An analytical survey of research since WWII that led to innovative therapeutic agents. For each of 32 drugs a review of the original scientific contributions associated with its discovery is presented. These chapters are followed by a computer analysis of important variables and finally by an interpretation and discussion of implications. Annotation c. Book News, Inc., Portland, OR (booknews.com)