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The Thalassaemia Syndromes Book

The Thalassaemia Syndromes
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The Thalassaemia Syndromes, In the new edition of this successful and authoritative book, the thalassaemias are reviewed in detail with respect to their clinical features, cellular pathology, molecular genetics, prevention and treatment. It is aimed at specialists in haematology in , The Thalassaemia Syndromes
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  • The Thalassaemia Syndromes
  • Written by author D. J. Weatherall, J. Clegg, R. Gibbons, Higgs, J. M. Old
  • Published by Wiley-Blackwell, 2001/05/02
  • In the new edition of this successful and authoritative book, the thalassaemias are reviewed in detail with respect to their clinical features, cellular pathology, molecular genetics, prevention and treatment. It is aimed at specialists in haematology in
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Authors

Authors and contributors
Preface to the fourth edition
Preface to the first edition
Acknowledgements
Pt. 1 Historical background
1 Historical perspectives: the many and diverse routes to our current understanding of the thalassaemias 3
Pt. 2 The biology of the thalassaemias
2 Human haemoglobin 65
3 Thalassaemia: classification, genetics and relationship to other inherited disorders of haemoglobin 121
4 The molecular pathology of the thalassaemias 133
5 The pathophysiology of the thalassaemias 192
6 Distribution and population genetics of the thalassaemias 237
Pt. 3 Clinical features of the thalassaemias
7 The [beta] thalassaemias 287
8 The [delta][beta] and related thalassaemias 357
9 The [beta] and [delta][beta] thalassaemias in association with structural haemoglobin variants 393
10 Hereditary persistence of fetal haemoglobin 450
11 The [alpha] thalassaemias and their interaction with structural haemoglobin variants 484
12 [alpha] Thalassaemia with mental retardation or myelodysplasia 526
13 Thalassaemia intermedia 550
Pt. 4 Diagnosis and management of thalassaemia
14 Avoidance and population control 597
15 Management and prognosis 630
16 The laboratory diagnosis of the thalassaemias 686
The future 727
References 733
App.: Addresses of patient support organizations 823
Index 827


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The Thalassaemia Syndromes, In the new edition of this successful and authoritative book, the thalassaemias are reviewed in detail with respect to their clinical features, cellular pathology, molecular genetics, prevention and treatment. It is aimed at specialists in haematology in , The Thalassaemia Syndromes

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The Thalassaemia Syndromes

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