Disinfection and Decontamination: Principles, Applications and Related Issues Book

Preface vii

Acknowledgments ix

Contributors xi

1 Perspectives on Infection Challenges and Solutions Gurusamy Manivannan 1

2 Sisyphus in the Microbial World Revisited: Global Governance, Antimicrobial Strategies, and Humanity's Health David P. Fidler 23

3 The Need for Safer and Better Microbicides for Infection Control Syed A. Sattar Susan Springthorpe 41

4 Microbiological Concerns in Non-Sterile Manufacturing Joseph Kirby Farrington Jim Polarine 59

5 New Technologies in Disinfection and Infection Control Jose A. Ramirez 73

6 Biocides: Modes of Action and Mechanisms of Resistance Gerald McDonnell 87

7 A Pragmatic Approach to Judicious Selection and Proper Use of Disinfectant and Antiseptic Agents in Healthcare Settings Vesna Suljagic 125

8 Extended Activity of Healthcare Antiseptic Products Jerry L. Newman Nancy E. Kaiser 155

9 Disinfectant Rotation in a Cleaning/Disinfection Program for Clean Rooms and Controlled Environments Scott V.W. Sutton 165

10 Reprocessing Flexible Endoscopes: Origin of Standards, Overview of Structure/Function, and Review of Recent Outbreaks Terri A. Antonucci Nicole Williams Nancy A. Robinson 177

11 Microbiological Testing of Disinfectants and Decontaminants for Critical Surfaces Daniel A. Klein 215

12 Regulatory Constraints on Disinfectants and Decontamination Michael G. Sarli 231

13 Biofilms: A Summarized Account and Control Strategies Kanavillil Nandakumar Kurissery R. Sreekumari 265

14 Consequences of Biofilms on Indwelling Medical Devices: Costs and Prevention John G. Thomas Lindsay Nakaishi Linda Corum 289

15 Infection-Resistant Implantable Devices: Biofilm Problems and Design Strategies Anthony W.Smith Semali Perera 339

16 Infections of Intracardiac Devices George A. Yesenosky Scott W. Sinner Steven P. Kutalek Allan R. Tunkel 373

17 Intrauterine Devices: Infections and Biofilms Ben M.J. Pereira Vikas Pruthi 395

18 Antimicrobial Urinary Catheters David J. Stickler Nora A. Sabbuba 415

19 Risk Factors for Postoperative Infectious Complications after Abdominal Surgery Patrick Pessaux Emilie Lermite 459

Authors 469

Index 481