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Biomarkers in Clinical Drug Development, Vol. 132 Book

Biomarkers in Clinical Drug Development, Vol. 132
Biomarkers in Clinical Drug Development, Vol. 132, Presenting applications in clinical development, pharmacokinetic/ pharmacodynamic modelling and clinical trial simulation, this reference studies the role of biomarkers in successful drug formulation and development., Biomarkers in Clinical Drug Development, Vol. 132 has a rating of 2 stars
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Biomarkers in Clinical Drug Development, Vol. 132, Presenting applications in clinical development, pharmacokinetic/ pharmacodynamic modelling and clinical trial simulation, this reference studies the role of biomarkers in successful drug formulation and development., Biomarkers in Clinical Drug Development, Vol. 132
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  • Biomarkers in Clinical Drug Development, Vol. 132
  • Written by author John Bloom
  • Published by Informa Healthcare, May 2003
  • Presenting applications in clinical development, pharmacokinetic/ pharmacodynamic modelling and clinical trial simulation, this reference studies the role of biomarkers in successful drug formulation and development.
  • Presenting applications in clinical development, pharmacokinetic/ pharmacodynamic modelling and clinical trial simulation, this reference studies the role of biomarkers in successful drug formulation and development. Doody Review Services
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Authors

Preface
Contributors
1Biomarkers in Clinical Drug Development: Definitions and Disciplines1
2The Clinical Laboratory and Collection of Biomarker Data11
3Using Imaging Biomarkers to Demonstrate Efficacy in Clinical Trials: Trends and Challenges31
4Markers for Cardiac Repolarization and Risk Assessment73
5Development and Application of Interspecies Biomarkers in Nonclinical Safety Evaluations97
6Validation of Assays for the Bioanalysis of Novel Biomarkers: Practical Recommendations for Clinical Investigation of New Drug Entities119
7Validation of Biomarkers as Surrogates for Clinical Endpoints149
8Biomarkers for Pharmacokinetic/Pharmacodynamic Modeling and Clinical Trial Simulations169
9Pharmacogenomic Biomarkers189
10Quality Assurance and Regulatory Compliance211
11Biomarker Strategies in Drug Development: Striking a Balance Between Opportunities and Liabilities235
12Partnerships in Biomarker Research247
13Clinical Operations: Business Principles for Biomarker Applications271
Index281


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