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Genomic and Molecular Neuro-Onocology Book

Genomic and Molecular Neuro-Onocology
Genomic and Molecular Neuro-Onocology, Written for a broad range of researchers and clinicians including oncologists, neurologists, pathologists, neuroscientists, residents, postdoctoral fellows, and others in related fields, this comprehensive reference documents cutting-edge advances in geno, Genomic and Molecular Neuro-Onocology has a rating of 3.5 stars
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Genomic and Molecular Neuro-Onocology, Written for a broad range of researchers and clinicians including oncologists, neurologists, pathologists, neuroscientists, residents, postdoctoral fellows, and others in related fields, this comprehensive reference documents cutting-edge advances in geno, Genomic and Molecular Neuro-Onocology
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  • Genomic and Molecular Neuro-Onocology
  • Written by author Wei Zhang
  • Published by Jones & Barlett Learning, November 2003
  • Written for a broad range of researchers and clinicians including oncologists, neurologists, pathologists, neuroscientists, residents, postdoctoral fellows, and others in related fields, this comprehensive reference documents cutting-edge advances in geno
  • Zhang and Fuller (U. of Texas M.D. Anderson Cancer Center, Houston) note the alarming rise in the incidence of brain tumors, though epidemiology is not otherwise discussed. Despite advances in understanding and treating some types of gliomas, tumors of th
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Preface
Foreword
Pt. IGenomic and Genetic Alterations in Gliomas1
Ch. 1Methylation and Genomic Damage in Gliomas3
Ch. 2Molecular and Clinical Aspects of 1p/19q Loss in Oligodendroglioma17
Ch. 3Functional Inactivation of p53 in Gliomas31
Ch. 4PTEN, A Tumor Suppressor Gene Frequently Mutated in Glioblastomas47
Ch. 5Molecular Genetics of the SWI/SNF Family Gene INI1 in Atypical Teratoid/Rhabdoid Tumors63
Pt. IIMolecular Alterations in Gliomas79
Ch. 6Molecular Markers in Diagnosis and Classification81
Ch. 7Molecular and Biological Determinants of Invasiveness and Angiogenesis in Central Nervous System Tumors97
Ch. 8Insulin-like Growth Factors and Insulin-like Growth Factor Binding Proteins in CNS Tumors119
Pt. IIIGenomics and Informatics131
Ch. 9Glioma Transcriptomes: Classifiers and Classification133
Ch. 10Tissue Microarrays: Applications in Neuro-Oncology Research149
Ch. 11Abnormal Regulation of RNA Splicing in Gliomas165
Ch. 12Chromosomal Imbalances in Oligodendroglial Tumors as Detected by Comparative Genomic Hybridization185
Ch. 13Statistical Considerations in the Design and Analysis of Microarray Experiments199
Ch. 14Transcriptome-Based Glioma Classification Using Informative Gene Set205
Pt. IVAnimal Models221
Ch. 15Mouse Models for Infiltrative Gliomas223
Ch. 16Dissecting Gliomagenesis Using Glial-Specific Transgenic Mouse Models233
Pt. VMolecular Therapeutics279
Ch. 17Gene-Based Therapy for Gliomas: Targeting the Cancer Genomes281
Ch. 18Therapeutic Targeting of the Molecular Pathways That Induce Brain Tumor Development303
Index333


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Genomic and Molecular Neuro-Onocology, Written for a broad range of researchers and clinicians including oncologists, neurologists, pathologists, neuroscientists, residents, postdoctoral fellows, and others in related fields, this comprehensive reference documents cutting-edge advances in geno, Genomic and Molecular Neuro-Onocology

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Genomic and Molecular Neuro-Onocology, Written for a broad range of researchers and clinicians including oncologists, neurologists, pathologists, neuroscientists, residents, postdoctoral fellows, and others in related fields, this comprehensive reference documents cutting-edge advances in geno, Genomic and Molecular Neuro-Onocology

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