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Ch. 1 | Water and Ocular Fluids: Physical Chemistry of Ocular Fluids | 1 |
Water | 1 | |
Weak Electrolytes and Buffers in Water | 3 | |
Ocular Fluids | 7 | |
Ch. 2 | Proteins: Essential Components of the Eye | 15 |
Crystallins | 22 | |
Rhodopsin and Cone Pigment Proteins | 33 | |
Mucous Glycoproteins | 40 | |
Collagen | 41 | |
Ch. 3 | Enzymes: Ocular Catalysts | 55 |
Michaelis-Menten Enzymes | 56 | |
Allosteric Enzymes | 60 | |
Enzyme Inhibation | 62 | |
Lysozyme | 64 | |
Na, K-ATPase | 68 | |
Lactate Dehydrogenase | 70 | |
Aldose Reductase | 75 | |
Matrix Metalloproteinases | 77 | |
Ch. 4 | Carbohydrates | 85 |
Energy Metabolism | 89 | |
Ocular Comparative Metabolism | 106 | |
Problems of Carbohydrate Transport and Metabolism: Diabetes and Galactosemia | 108 | |
Structural Carbohydrates | 123 | |
Ch. 5 | Lipids | 133 |
Cell Membranes | 142 | |
Precorneal Tear Film Lipids | 147 | |
Lipids of the Retina | 149 | |
Vitamin A | 150 | |
Glycolopid Storage Diseases and Vision | 153 | |
Ch. 6 | Hormones | 159 |
Hormone General Functions: Chemical Micromanagers | 159 | |
Plasma Membrane Hormones and Their Receptors: Mechanisms | 165 | |
Light Transduction: A cGMP Mechanism | 171 | |
Graves' Disease: Autoimmune Mischief with Thyroid Hormones | 176 | |
DNA Binding Hormones: Mechanism | 179 | |
Paracrine Hormones | 182 | |
Ch. 7 | Nucleic Acids | 191 |
Nucleic Acid Biochemistry | 191 | |
Mutations to DNA and to Nucleic Acid Processing | 210 | |
Molecular Biology of the Crystallins | 213 | |
Viral Intervention in the Cornea | 220 | |
Potential Gene Therapy of Rentinal Disease | 223 | |
Ch. 8 | Ocular Neurochemistry | 231 |
Neurotransmitters and Receptor Proteins and Their Properties (Including Ocular Autonomic Functions) | 234 | |
Neurochemistry of the Retina | 239 | |
Ocular Neurochemical Pathology | 245 | |
Ch. 9 | Ocular Immunochemistry | 249 |
Review of Immunoglobulins | 249 | |
Ocular Immunoglobulins | 256 | |
Complement | 257 | |
Complement of the Eye | 260 | |
Inflammation | 260 | |
Ocular Inflammation | 266 | |
Ch. 10 | Ocular Biochemical Degradation: Aging and Pathological Processes | 271 |
Cellular Apoptosis | 271 | |
Liquefaction of the Vitreous | 275 | |
Chemical Burns of the Cornea | 277 | |
Glossary | 283 | |
Answers to Problems | 306 | |
Index | 313 |
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