Adrenal in Toxicology: Target Organ and Modulator of Toxicity Book

	Preface
	Contributors
Sect. 1	Introduction to Adrenal Gland Involvement in Toxicology	1
1	An overview of adrenal gland involvement in toxicology: from target organ to stress and glucocorticosteroid modulation of toxicity	3
Sect. 2	General Endocrinology, Pharmacology and Pathology of the Adrenal Gland Related to Species, Sex and Age and Glucocorticosteroid Actions	21
2	Adrenal morphology and hormone synthesis and regulation	23
3	Transport, actions and metabolism of adrenal hormones and pathology and pharmacology of the adrenal gland	53
4	Molecular and systems pharmacology of glucocorticosteroids	81
Sect. 3	The Adrenal Gland as a Target Organ	129
5	The adrenal cortex as a toxicological target organ	131
6	The adrenal medulla as a toxicological target organ	165
Sect. 4	Adrenocortical and Glucocorticosteroid Modulation of Toxicity	183
7	Glucocorticosteroid modulation of toxicity	185
8	Glucocorticosteroids: deleterious effects on neurons and potential exacerbation of environmental neurotoxicity	205
9	Glucocorticosteroids, stress and developmental toxicology	223
10	Glucocorticosteroids and immunotoxicity	243
Sect. 5	Clinical Interfaces: Adrenal and Corticosteroid Involvement in Human Toxicology and Extrapolation to Man	259
11	Corticosteroid adverse effects and drug interactions in man	261
12	Adverse drug reactions and the adrenal glands: a pharmacoepidemiological approach	279
13	Experimental adrenal toxicity: significance of findings and relevance to man	301
	Index	307