Kelley's Textbook of Rheumatology Online: Webstart DVD-ROM Book

VOLUME I

Section I: Structure and Function of Bone, Joints, and Connective Tissue
1. Biology of the Normal Joint
2. Collagen and Elastin
3. Matrix Glycoproteins and Proteoglycans in Cartilage
4. Proteinases and Matrix Degradation
5. Muscle: Anatomy, Physiology, and Chemistry
6. Biomechanics of Joints

Section II: Cells Involved in Autoimmune Diseases and Inflammation
7. Antigen Presenting Cells
8. Innate Immunity
9. T Lymphocytes
10. B Cells
11. Synoviocytes
12. Fibroblast Function and Fibrosis
13. Chondrocytes
14. Neutrophils and Eosinophils
15. Platelets and Rheumatic Diseases

Section III: Effector mechanisms in Autoimmunity and Inflammation
16. Autoimmunity
17. Genetics of Rheumatic Diseases
18. Signal Transduction in Rheumatic Diseases
19. Rheumatoid Factor
20. Antinuclear Antibodies
21. Immune Complexes
22. Complement System
23. Prostaglandins, Leukotrienes, and Related Compounds
24. Recruitment of Cells and Angiogenesis
25. Cytokines
26. Apoptosis

Section IV: Broad Issues in the Approach to Rheumatic Diseases
27. Epidemiology of the Rheumatic Diseases
28. Economic Burden of Rheumatic Diseases
29. Assessment of Health Outcomes
30. Development, Execution, and Analysis of Clinical Trials
31. Occupational and Recreational Musculoskeletal Disorders
32. Alternative Care for Arthritis and Related Musculoskeletal Diseases

Section V: Evaluation of Generalized and Localized Symptoms
33. History and Physical Examination of the Musculoskeletal System
34. Monarticular Arthritis
35. Polyarticular Arthritis
36. Fibromyalgia: A Chronic Pain Syndrome
37. Neck Pain
38. Shoulder Pain
39. Low Back Pain
40. Hip and Knee Pain
41. Ankle and Foot Pain
42. Hand and Wrist Pain
43. Temporomandibular Joint Pain
44. The Eye and Rheumatic Disease
45. The Skin and Rheumatic Diseases

Section VI: Diagnostic Tests and Procedures in Rheumatic Diseases
46. Synovial Fluid Analyses, Synovial Biopsy, and Synovial Pathology
47. Arthrocentesis and Injection of Joints and Soft Tissues
48. Arthroscopy
49. Laboratory Evaluation of Inflammatio
50. Biological Markers
51. Imaging of Bones, Joints, and Connective Tissue

Section VII: Modalities of Therapy in Rheumatic Diseases: Non-pharmacologic Interventions
52. Education of Patients
53. Psychosocial Management of the Rheumatic Diseases
54. Nutrition and Rheumatic Diseases
55. Rehabilitation of Patients with Rheumatic Diseases

Section VIII: Drug Therapy for Rheumatic Diseases
56. Nonsteroidal Anti-inflammatory Drugs
57. Glucocorticoid Therapy
58. Second-line Agents: Sulfasalazine, Anti-malarials, Gold Salts, and D-penicillamine
59. Methotrexate, Leflunomide, and Combination Therapies
60. Immunoregulatory Drugs
61. Anti-cytokine Therapies
62. Emerging Therapies
63. Pharmacology and the Elderly
64. Chronic Musculoskeletal Pain

VOLUME 2

Section IX: Rheumatoid Arthritis
65. Etiology and Pathogenesis of Rheumatoid Arthritis
66. Clinical Features of Rheumatoid Arthritis
67. Treatment of Rheumatoid Arthritis
68. Felty's Syndrome
69. Sjogren's Syndrome

Section X: Spondyloarthropathies
70. Ankylosing Spondylitis
71. Reiter's Syndrome, Undifferentiated Spondyloarthropathy and Reactive Arthritis
72. Psoriatic Arthritis
73. Enteropathic Arthritis

Section XI: Systemic Lupus Erythematosus and Related Syndromes
74. Pathogenesis of SLE
75. Clinical Manifestations of Systemic Lupus Erythematosus
76. Management of Systemic Lupus Erythematosus
77. Antiphospholipid Antibody Syndrome

Section XII: Mixed Connective Tissue Disease, Scleroderma, and Inflammatory Myopathies
78. Mixed Connective Tissue Disease and Other Overlap Syndromes
79. Scleroderma and Raynaud's Disease
80. Inflammatory Diseases of Muscle and Other Myopathies

Section XIII: Vasculitis

81. The Classification and Epidemiology of Systemic Vasculitis
82. Giant Cell Arteritis, and Polymyalgia Rheumatica,
83. Anti-Neutrophil Cytoplasmic Antibody (ANCA) Associated Vasculitis: Wegener's Granulomatosis, Microscopic Polyangitis and Churg Strauss Syndrome
84. Polyarteritis and Related Disorders
85. Cutaneous Small-Vessel Vasculitis
86. Behcet's Disease

Section XIV: Crystal-induced Inflammation
87. Gout and Hyperuricemia
88. Diseases Associated with Articular Deposition of Calcium Pyrophosphate Dihydrate and Basic Calcium Phosphate Crystals

Section XV: Bone, Cartilage, and Heritable Connective Tissue Disorders
89. Biology, Physiology, and Morphology of Bone
90. Metabolic Bone Disease
91. Pathogenesis of Osteoarthritis
92. Clinical Features of Osteoarthritis
93. Management of Osteoarthritis
94. Relapsing Polychondritis
95. Heritable Disorders of Structural Proteins

Section XVI: Rheumatic Diseases of Childhood
96. Juvenile Rheumatoid Arthritis
97. Systemic Lupus Erythematosus, Juvenile Dermatomyositis, Scleroderma and Vasculitis

Section XVII: Infection and Arthritis
98. Arthritis Caused by Bacteria or Their Components
99. Lyme Disease
100. Mycobacterial and Fungal Infections
101. Rheumatic Manifestations of Human Immunodeficiency Virus Infection
102. Viral Arthritis
103. Acute Rheumatic Fever and Post-Streptoccocal Arthritis

XVIII: Arthritis Accompanying Systemic Diseases
104. Amyloidosis
105. Sarcoidosis
106. Iron Storage Disease
107. Hemophilic Arthropathy
108. Hemoglobinopathies and Arthritis
109. Arthritis Accompanying Endocrine and Metabolic Disorders
110. Hypertrophic Osteoarthropathy
111. Musculoskeletal Syndromes in Malignancy
112. Familial Auto-inflammatory Syndromes

XIX: The Common Ground of Rheumatology and Orthopaedic Surgery
113. Tumors and Tumor-like Lesions of Joints
114. Osteonecrosis
115. Introduction to Surgical Management of Patients with Arthritis
116. Principles of Reconstructive Surgery for Arthritis