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Clinical Measurement In Drug Evaluat Book

Clinical Measurement In Drug Evaluat
Clinical Measurement In Drug Evaluat, Internationally renowned authorities from diverse fields present the principles and practice regarding the measurement of drug effects in humans and its role in the analysis and development of new chemical entities. The main thrust is on surrogate endpoin, Clinical Measurement In Drug Evaluat has a rating of 3.5 stars
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Clinical Measurement In Drug Evaluat, Internationally renowned authorities from diverse fields present the principles and practice regarding the measurement of drug effects in humans and its role in the analysis and development of new chemical entities. The main thrust is on surrogate endpoin, Clinical Measurement In Drug Evaluat
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  • Clinical Measurement In Drug Evaluat
  • Written by author Nimmo
  • Published by Wiley, John & Sons, Incorporated, August 1995
  • Internationally renowned authorities from diverse fields present the principles and practice regarding the measurement of drug effects in humans and its role in the analysis and development of new chemical entities. The main thrust is on surrogate endpoin
  • Internationally renowned authorities from diverse fields present the principles and practice regarding the measurement of drug effects in humans and its role in the analysis and development of new chemical entities. The main thrust is on surrogate endpoin
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Preface
1A regulatory authority's opinion about surrogate endpoints3
2What to measure in dementia23
3Twenty-four-hour ambulatory arterial (blood) pressure measurement and the assessment of antihypertensive drug efficacy45
4Potential measurements in patients with osteoporosis63
5Are bronchial challenge studies indicators of antiasthmatic activity?77
6Measurements of blood rheology for the evaluation of pharmacological agents99
7Platelet function tests121
8Assessment of the effects of drugs on the peripheral vasculature135
9What are the valid measurements of drug efficacy in patients with intermittent claudication?151
10Bias and confounding in clinical studies175
11What does Good Clinical Practice have to say about clinical measurement?189
12Measurement of bioequivalence and its relevance to the clinical situation195
13The 'clinical trial' of the clinical trial205
14Patient compliance with prescribed drug regimens: overview of the past 30 years of research213
15Prediction of drug interactions: implications of recent advances in drug metabolism231
16What number of patients is necessary to establish drug safety?245
17Accuracy of adverse data from post-marketing studies and the influence on extension of licensed indications267
18Controlled clinical trials: contribution to drug safety281
19Predicting adverse drug reactions291
20Interactions in first-pass metabolism and variability in drug response301
Index315


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