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Greene's Protective Groups in Organic Synthesis Book

Greene's Protective Groups in Organic Synthesis
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  • Greene's Protective Groups in Organic Synthesis
  • Written by author Peter G. M. Wuts
  • Published by Wiley, John & Sons, Incorporated, November 2006
  • The Most Comprehensive Guide to Protective Groups in Organic Synthesis Currently Available For more than twenty-five years, Protective Groups in Organic Synthesis has been the definitive guide for organic chemists in designing synthetic r
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Authors

Preface to the Fourth Edition.

Preface to the Third Edition.

Preface to the Second Edition.

Preface to the First Edition.

Abbreviations.

1. The Role of Protective Groups in Organic Synthesis.

2. Protection for the Hydroxyl Group, Including 1,2- and 1,3-Diols.

Ethers.

Esters.

Protection for 1,2- and 1,3-Diols.

3. Protection for Phenols and Catechols.

Protection for Phenols.

Ethers.

Silyl Ethers.

Esters.

Carbonates.

Aryl Carbamates.

Phosphinates.

Sulfonates.

Protection for Catechols.

Cyclic Acetals and Ketals.

Cyclic Esters.

Protection for 2-Hydroxybenzenethiols.

4. Protection for the Carbonyl Group.

Acetals and Ketals.

Miscellaneous Derivatives.

Monoprotection of Dicarbonyl Compounds.

5. Protection for the Carboxyl Group.

Esters.

Amides and Hydrazides.

Protection of Boronic Acids.

Protection of Sulfonic Acids.

6. Protection for the Thiol Group.

Thioethers.

Thioesters.

Miscellaneous Derivatives.

7. Protection for the Amino Group.

Carbamates.

Amides.

Special —NH Protective Groups.

Protection for Imidazoles, Pyrroles, Indoles, and other Aromatic Heterocycles.

Protection for the Amide —NH.

Protection for the Sulfonamide —NH.

8. Protection for the Alkyne —CH.

9. Protection for the Phosphate Group.

Some General Methods for Phosphate Ester Formation.

Removal of Protective Groups from Phosphorus.

Alkyl Phosphates.

Phosphates Cleaved by Cyclodeesterifi cation.

Benzyl Phosphates.

Phenyl Phosphates.

Photochemically Cleaved Phosphate Protective Groups.

Amidates.

Miscellaneous Derivatives.

10. Reactivities, Reagents, and Reactivity Charts.

Reactivities.

Reagents.

Reactivity Charts.

1 Protection for the Hydroxyl Group: Ethers.

2 Protection for the Hydroxyl Group: Esters.

3 Protection for 1,2- and 1,3-Diols.

4 Protection for Phenols and Catechols.

5 Protection for the Carbonyl Group.

6 Protection for the Carboxyl Group.

7 Protection for the Thiol Group.

8 Protection for the Amino Group: Carbamates.

9 Protection for the Amino Group: Amides.

10 Protection for the Amino Group: Special —NH Protective Groups.

11 Selective Deprotection of Silyl Ethers.

Index.


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