Portfolio, Program, and Project Management in the Pharmaceutical and Biotechnology Industries Book

Preface ix

Acknowledgments xi

About the Authors xiii

Part 1 The Life Science Industry Context for Portfolio, Program, and Project Management

1 A Review of Project Management in Life Science Industry Sectors Thomas R. Dunson 3

2 The Impact of Organizational Size on Drug Project Management Eric Morfin 21

3 Drug Development in Biotechnology and How We Can Do It Better Susan Linna 33

Part 2 The Portfolio, Program, and Project Management Approaches and Processes

4 An Overview of the Organization and Processes of Portfolio, Program, and Project Management Pete Harpum 53

5 Portfolio Management in the Pharmaceutical Industry: Balancing Corporate Need with the Reality of Delivering Products to the Market John Bennett 59

6 Program Management in Drug Development Pauline Stewart-Long 85

7 Project Control Martin Powell 101

8 Managing Uncertainty in Drug Projects Pete Harpum Thomas R. Dunson 135

9 Managing Drug Safety Risk Thomas R. Dunson Eric Morfin 155

10 Developing Program Strategy Pete Harpum 175

11 Developing Products with "Added Value" Trevor J. Brown Stephen Allport 197

Part 3 Integrating the Processes

12 Integrated Business Processes to Support Cross-Functional Drug Development Martin D. Hynes III 227

13 Integrated Drug Development From Gradle to Grave and from Lab to Market Stephen Allport Terry Cooke-Davies 239

14 The Development of P³M Capability in Drug Development Organizations John Arrowsmith Patrick Grogan Bob Moore 259

15 Implementing Portfolio, Program, and Project Management Best Practices in Drug Development Organizations Pete Harpum Ashley Jamieson Inge Fisher 287

Bibliography 311

Index 313