Glial Cell Function (Paperback) Book

	List of Contributors
	Preface
Sect. I	Glial cell development: origin and phenotype acquisition
1	Regulation of genes involved in Schwann cell development and differentiation	3
2	Regulation of radial glia phenotype	13
3	Astrocytic intermediate filaments: lessons from GFAP and vimentin knock-out mice	23
4	Glial cells: a target for steroid hormones	31
5	Thyroid hormone role in nervous system morphogenesis	41
6	Early origin and colonization of the developing central nervous system by microglial precursors	51
7	Microglia: its development and role as a neuropathology sensor	61
8	Colonisation of the human central nervous system by microglia: the roles of chemokines and vascular adhesion molecules	81
Sect. II	Myelination, demyelination and remyelination
9	Astrocyte influence on oligodendrocyte progenitor migration	97
10	Tenascin-R as a regulator of CNS glial cell function	103
11	Process extension and myclin sheet formation in maturing oligodendrocytes	115
12	Recent advances in human perinatal white matter injury	131
13	Models for demyclination	149
14	The response of adult oligodendrocyte progenitors to demyclination in EAE	165
15	Neural precursors and demyelinating diseases	175
16	What roles do growth factors play in CNS remyelination?	185
Sect. III	Glial-neuronal interactions
17	Molecular mechanisms of interactions between radial glia and neurons	197
18	Connexins and gap junctional communication in astrocytes are targets for neuroglial interaction	203
19	Glial signalling in response to neuronal activity in the leech central nervous system	215
20	Glial cells as active partners in synaptic functions	227
21	Calcium signaling in retinal glial cells and its effect on neuronal activity	241
22	Neuron-astrocyte cross-talk during synaptic transmission: physiological and neuropathological implications	255
23	Regulation of glutamate transporters in health and disease	267
24	Ionotropic glutamate receptors in astrocytes	287
25	Metabotropic glutamate receptors in freshly isolated astrocytes from rat hippocampus	301
26	The pleiotropin/midkine family of cytokines: role in glial-neuronal signalling	313
27	The nitric oxide/cyclic GMP system in astroglial cells	325
28	Glial diffusion barriers during aging and pathological states	339
Sect. IV	Glial response to injury and molecular mechanisms of neuroprotection
29	Glial cell responses to lipids bound to albumin in serum and plasma	367
30	Glial activation in the immature rat brain: implication of inflammatory transcription factors and cytokine expression	375
31	Role of nuclear factor kappa B in neuropathological mechanisms	391
32	Ischemia: astrocytes show their sensitive side	405
33	Adaptative responses of spinal astrocytes to oxidative stress	413
34	Glial expression of heat shock proteins (HSPs) and oxygen-regulated proteins (ORPs)	427
35	Nitric oxide-mediated mitochondrial impairment in neural cells: a role for glucose metabolism in neuroprotection	441
36	Keeping TNF-induced apoptosis under control in astrocytes: PEA-15 as a 'double key' on caspase-dependent and MAP-kinase-dependent pathways	455
37	Astroglia play a key role in the neuroprotective actions of estrogen	469
Sect. V	Inflammation and cytokine signalling
38	Cytokine-mediated inflammation and signaling in the intact central nervous system	481
39	Inhibition of nitric oxide production for down-regulation of CNS inflammation and demyelination	499
40	Chemokine targets in acute brain injury and disease	507
41	Microglial chemokines and chemokine receptors	525
42	The role of chemokines and chemokine receptors in CNS inflammation	533
43	Signals regulating neurotrophin expression in glial cells	545
44	Microglial signalling cascades in neurodegenerative disease	555
Sect. VI	Repair and regeneration
45	Transcription factors in nerve regeneration	569
46	The role of astrocytes in axonal regeneration in the mammalian CNS	587
47	Chondroitin sulphate proteoglycans: inhibitory components of the glial scar	611
48	Axon regeneration across the dorsal root entry zone	621
49	Transplants of olfactory bulb ensheathing cells promote functional repair of multiple dorsal rhizotomy	641
50	Regulatable and cell-type specific transgene expression in glial cells: prospects for gene therapy for neurological disorders	655
Sect. VII	Therapeutical approaches to tumours, viral and prion infections
51	Immune escape of gliomas	685
52	Clinical trials of adenoviral-mediated suicide gene therapy of malignant gliomas	699
53	Gene therapy of glioblastomas: from suicide to homicide	711
54	Glial cells as targets of viral infection in the human central nervous system	721
55	Pathogenesis of prion diseases: possible implications of microglial cells	737
	Subject Index	751