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Advanced Methods of Pharmacokinetic and Pharmacodynamic Systems Analysis, Vol. 1 Book

Advanced Methods of Pharmacokinetic and Pharmacodynamic Systems Analysis, Vol. 1
Advanced Methods of Pharmacokinetic and Pharmacodynamic Systems Analysis, Vol. 1, , Advanced Methods of Pharmacokinetic and Pharmacodynamic Systems Analysis, Vol. 1 has a rating of 3 stars
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  • Advanced Methods of Pharmacokinetic and Pharmacodynamic Systems Analysis, Vol. 1
  • Written by author David Z. DArgenio
  • Published by Springer-Verlag New York, LLC, November 2007
  • Advanced Methods of Pharmacokinetic and Pharmocodynamic Systems Analysis Volume 3 is vital to professionals and academicians working in drug development and bioengineering. Both basic and clinical scientists will benefit from this work.This book conta
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Preface
Physiological modeling of the small intestine in drug absorption3
Intracellular metabolism of Lamivudine33
Mechanism-based pharmacodynamic modeling for prediction of exposure response49
Mechanism-based PK/PD modeling of Digoxin : role of receptor heterogeneity and postreceptor events67
Pharmacodynamics and pharmacogenomics of corticosteroids : microarray studies85
Bayesian inference in physiologically-based pharmacokinetic modeling : application to anticancer drug development105
Monte Carlo parametric expectation maximization (MC-PEM) method of analyzing population pharmacokinetic/pharmacodynamic data135
Application of Markov chain Monte Carlo methods to inverse problems in PK/PD165
Regenerative Markov chain Monte Carlo methods for pharmacokinetic/pharmacodynamic estimation179
Vizstruct : a multidimensional visualization algorithm for gene expression197
Modeling and simulation of effects of adherence, pharmacokinetic, and pharmacodynamic characteristics in development of resistance to HIV regimens in treatment-naive patients211
Mechanistic PK/PD modeling of antiretroviral therapies in AIDS clinical trials221
Dose individualization for high-dose anti-cancer chemotherapy239
Toward model-based chemotherapy treatment design255
Control of uncertain pharmacodynamic systems275
Contributors295
Participants305
Index317


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