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Taxus Book

Taxus
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Taxus, Taxol, originally derived from the North American yew tree in 1971, is well-know worldwide as a powerful anticancer agent. Mechanistically, it has a unique microtubule stabilizing activity, and was clinically developed as a therapeutic agent in the treatm, Taxus
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  • Taxus
  • Written by author Edited by H. Itokawa
  • Published by Taylor & Francis, Inc., 4/11/2003
  • Taxol, originally derived from the North American yew tree in 1971, is well-know worldwide as a powerful anticancer agent. Mechanistically, it has a unique microtubule stabilizing activity, and was clinically developed as a therapeutic agent in the treatm
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Book Categories

Authors

List of contributors
Preface to the series
Preface
1 Introduction 1
2 Biosynthesis of taxoids 19
3 Taxoids occurring in the genus Taxus 35
4 Physical methods for identification of the structures of taxoids 79
5 Plant tissue culture of taxoids 134
6 The commercial cultivation of Taxus species and production of taxoids 151
7 Analytical aspects of taxoids 179
8 Chemistry of taxol and related taxoids 213
9 Total synthesis of taxoids 245
10 Structure-activity relationship of taxoids 298
11 Preclinical and clinical studies of the taxanes 387
12 Paclitaxel content of yews in Ireland 436
Name index 443
Subject index 449


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Taxus, Taxol, originally derived from the North American yew tree in 1971, is well-know worldwide as a powerful anticancer agent. Mechanistically, it has a unique microtubule stabilizing activity, and was clinically developed as a therapeutic agent in the treatm, Taxus

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