Handbook of the Biology of Aging Book

Part I: Basic Aging Processes

1. The Genetic Network of Lifespan Extension by Dietary Restriction - Eric Greer and Anne Brunet

2. Role of the Somatotropic Axis in Mammalian Aging - Holly M.Brown-Borg

3. Mechanisms of Mitochondrial Free Radical Production and their Relationship to the Aging Process - Casey L. Quinlan, Jason R. Treberg, and Martin D. Brand

4. Aging and Apoptosis in Muscle - Stephen E. Alway, Michael R. Morissette, and Parco M. Siu

5. Aging and Adipose Tissue - Roberta Florido, Tamara Tchkonia, and James L. Kirkland

6. Aging of Stem Cells: Intrinsic Changes and Environmental Influences - Ling Liu and Thomas A. Rando

7. Leukocyte Telomere Dynamics, Human Aging and Lifespan - Abraham Aviv

8. An Unbiased Appraisal of the Free Radical Theory of Aging - Michael Lustgarten, Florian L. Muller, and Holly Van Remmen

9. TOR: A Conserved Nutrient-Sensing Pathway that Determines Life-Span Across Species - Pankaj Kapahi and Lutz Kockel

10. Comparative Genetics of Aging - George L. Sutphin and Matt Kaeberlein

11. Sirtuins in Aging and Age-Related Diseases - Marcia C. Haigis and David A. Sinclair

12. Inflammation in Aging Processes: An Integrative and Ecological Perspective - Caleb E. Finch

13. Protein Homeostasis and Aging - Susmita Kaushik and Ana Maria Cuervo

Part II: Medical Physiology of Aging

14. Terminal Weight Loss, Frailty, and Mortality - Edward J. Masoro

15. Human Brain Myelination Trajectories Across the Lifespan: Implications for CNS Function and Dysfunction - Jonathan E. Sherin and George Bartzokis

16. Aging and the Cerebral Microvasculature: Clinical Implications and Potential Therapeutic Interventions - Farzaneh A. Sorond and Lewis A. Lipsitz

17. Aging and Insulin Secretion - Jeffrey B. Halter

18. Cardiovascular Effects of Aging in Primates - Gender Differences - Hongyu Qiu, Christophe Depre, Dorothy E. Vatner, and Stephen F. Vatner

19. Cerebral Vascular Dysfunction with Aging - Frank M. Faraci

20. Pulmonary Function in Aging Humans - Nigel A.S. Taylor

21. Calorie Restriction in Nonhuman and Human Primates - Luigi Fontana, Ricki J. Colman, John O. Holloszy, and Richard Weindruch

22. Age-related Changes in Thermoreception and Thermoregulation - Eus J.W. Van Someren

23. Sex Differences in Longevity and Aging - Steven N. Austad